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This manuscript introduces the basic principles of left ventricular mass (LV mass) estimation by echocardiography, focusing on the potential limitations and discrepancies of such measurement, in order to provide the appropriate background for understanding the rather complex issue of defining the cut-off values for LVH diagnosis .LV Mass = 0.8 x (1.04 x (((LVEDD + IVSd +PWd) 3 - LVEDD 3))) + 0.6; LVMI (LV Mass Indexed to Body Surface Area) = LV Mass / BSA; RWT (Relative Wall Thickness) = 2 x PWd / LVEDD; BSA (Mosteller) = (((Height in cm) x (Weight in kg))/ 3600) ½; Reference Ranges for LV Mass Indexed To BSA (g/m 2)
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Two-dimensional echocardiographic measurement of LV wall thickness in combination with geometric formulas to calculate and convert myocardial volume to myocardial mass provides a reproducible, quantitative, noninvasive assessment of LV mass that is more accurate than determination of mass by electrocardiography.
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Assessment of LV function with M-mode or 2-dimensional (2-D) echocardiography (Figure 2A) can be performed in the parasternal long- and short-axis views by placing the calipers perpendicular to the ventricular long axis. Change in LV cavity dimensions during systole can be used to calculate LV fractional shortening and ejection fraction.
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